This unit covers topics from the rapidly developing field of biological and medicinal inorganic chemistry with a particular emphasis on the fundamental inorganic chemistry that determines the diverse roles of metal ions in biological systems. Some of the important metalloproteins to be covered in detail are those containing iron, copper, zinc, calcium and manganese. Techniques for elucidating the structures of biological macromolecules (e.g. proteins and DNA) and their interaction with other molecules are covered including X-ray crystallography, NMR, ESR and X-ray absorption spectroscopy. Some applications of metals in medicine are covered including metal-based anticancer drugs and... -- Course Website
Instructor: Professor George Koutsantonis
Prerequisites: CHEM2210 Structure Determination and Physical Chemistry