This unit will introduce students to the different mechanisms of action by which drugs exert their biological activity. It will address the interactions between endogenous ligands and drugs with their receptors, enzymes or nucleic acids, and the way that drugs mimic, oppose or modify those interactions. Students will be introduced to the scope of medicinal chemistry techniques used in contemporary drug discovery.This will involve the study of: G-protein coupled receptors other Receptor types ion Channels nuclear Hormone Receptors drugs interacting with Oligonucleotides enzyme and Enzyme Inhibition -- Course Website
Instructor: Dr David Manallack
Prerequisites: PSC2011 Pharmaceutical biochemistry<br/>PSC2121 Synthetic chemistry I
