The role of metals in life. Coordination chemistry in biological (aqueous) environments. Structure and function of enzymes containing heavy metals. Enzymatic reactions involving metal centres: carbonic anhydrase and carboxypeptidase. Iron-based proteins (hemoglobin and myoglobin) and oxygen transport. Mitochondrial respiration: redox chemistry of iron complexes in cytochromes. <br/><br/>Principles of molecular recognition; chemical sensor design and applications; Bioelectrochemistry. Biosurfaces.<br/><br/>Agricultural chemicals: plant growth regulators, defoliants and dessicants; pesticides.<br/><br/>Laboratory experiments related to the biological chemistry topics in the unit. -- Course Website
Prerequisites: 313998 (v.1)<br/> Biological Chemistry 222<br/> <br/> <br/><br/> <br/> OR<br/><br/> <br/> 312493 (v.2)<br/> Biological Chemistry 221<br/> <br/> or any previous version