This unit provides students with understanding of the role of genetic factors in the causation of human disease. The emphasis is on genetic tools used to aid diagnosis, prognosis and prevention of primary and secondary consequences of genetic disease. The unit covers basic principles of chromosome structure and function, Mendelian patterns of inheritance and population genetics, single gene disorders, multifactorial diseases, chromosomal and somatic cell genetic disorders and mitochondrial diseases. Clinical applications of genetic testing include diagnostic testing; predictive genetic testing; genotyping to predict responses to, or side effects from, drugs; mutation carrier screening;... -- Course Website
Instructor: Winthrop Professor David Ravine
Prerequisites: GENE2230 Molecular Genetics