This unit builds on the previous unit "Chemical Properties of Drug Molecules" to provide students with an understanding of the basis of drug action - efficacy. The consequences of drug binding to cell-surface receptors and enzymes will be considered at a structural level.This will involve: drug targets receptor activation - efficacy and affinity chemistry of drug-receptor interactions newer / emerging drug classes - particularly "biologicals" - protein therapeutics pharmacology in action - practical application of principles of affinity, efficacy and potency. -- Course Website
Instructor: Dr Paul White (Parkville); Dr Tang Kim San (Sunway)
