Selective toxicity - scope of antimicrobial chemotherapy. Chemotherapy versus Pharmacodynamics. Principles of selective toxicity - distribution, comparative biochemistry, comparative cytology. Classifications of antibiotics. Principles of treatment - clinical diagnosis; bacteriological diagnosis; place of chemotherapy in medicine; considerations relevant to effective antibiotic use; reasons for treatment failure. Investigations of the mechanism of action, spectrum, absorption, distribution, metabolism and excretion and adverse events of the major classes of antimicrobial agents including: Sulfonamides/Trimethoprim; Penicillins, Cephalasporins and other Beta-lactam drugs; Aminoglycosides;... -- Course Website
Prerequisites: 311030 (v.1)<br/> Immunology and Infectious Diseases for Pharmacists 221<br/> <br/> or any previous version<br/> <br/> <br/><br/> <br/> OR<br/><br/> <br/> 11677 (v.3)<br/> Pharmaceutical Biology 233<br/> <br/> or any previous version
